|Gastrointestinal Disease due to Sustained Strenuous Exercise|
Strenuous exercise is associated in humans, horses, and dogs with the development of gastrointestinal disease, including diarrhea, cramping, and ulceration. Human marathon runners have up to an 80% prevalence of gastrointestinal bleeding, and racing sled dogs have recently been found to have a 50% prevalence of subclinical gastric ulcers.
In severe cases, the disease can be exercise limiting or even life threatening. The goals of these studies are to determine the mechanisms by which exercise leads to gastrointestinal disease and develop methods to prevent such disease.